Maslinic Acid
Product Name: Maslinic acid
Botanical Source:Olea europaea L.
Part used: Fruit
Specification: Maslinic acid 10%,30%,60%, 98% HPLC
CAS No.: 4373-41-5
Appearance: Light yellow powder
Molecular Formula: C30H48O4
Molecular Weight: 472.7
Pharmacological action: Anti - tumor, anti - HIV, hawthorn acid can cause the spread of HIV in the body to reduce the risk of 80%. anti-inflammatory, antibacterial.
Scientists at the University of Granada in Spain found that Maslinic Acid can inhibit serine protease, HIV is using this enzyme will itself from infected cells to the external release and spread to the virus infected systemic.
Introduction
Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in the Mediterranean diet. In recent years, several studies have proved that maslinic acid exerts a wide range of biological activities, i.e. antitumor,
antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. Experimental models used for the assessment of maslinic acid effects include established cell lines, which have been often used to elucidate the underlying mechanisms of action, and also animal models of different disorders, which have confirmed the effects of the triterpene in vivo.
Aslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response.
Maslinic acid extracted from notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative agent against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM and CEM/ADR5000) cells (IC50 = 7 µM and 9 µM respectively).1,2,3,4 Maslinic acid · s antiproliferative activity likely comes from the induction of an oxidative apoptotic pathway, causing cell cycle and cytoskeleton alterations. Maslinic acid has been found to attenuate intracellular oxidative stress via inhibition of NO and H2O2 production and reduction of pro-inflammatory cytokine generation in murine macrophages.5 Recently maslinic acid has been found to inhibit the spread of the HIV virus by inhibiting the replication of a primary HIV-1 isolate as well as decreased the cytopathic effect and p24 antigen levels in MT2 cells.6
Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. Maslinic acid used was a white powder comprising 98% maslinic acid and 2% of oleanolic acid. This extract was stable when stored at 4 ºC It was dissolved before use at 10 mg/ml in 25% DMSO and 75% PBS. A stock solution was frozen and stored at -20 ºC.
Function:
Anti-oxidant
Anti-inflammatory
Anti-microbial
Anti-viral activities
Providing significant natural defense against colon-cancer
Restrain the conglomeration of blood platelet
As a dietary supplement to promote muscle growth
Reducing blood fat and pressure.
Be beneficial for diabetes
Inhibiting the spread of the HIV virus
KINGHERBS' main products as below:
1.5-HTP
2. Acai Berry Extract
3. Acacia Catechu Extract
4. Allium cepa / Onion Extract
5. Aronia melanocarpa Extract
6. Artemisinin
7. Artichoke Extract
8. Astilbin
9. Apple Root Extract
10. Acerola Cherry Extract
11. Banaba Leaf Extract
12. Birch Leaf Extract
13. Birch Bark Extract
14. Bilberry Extract
15. Black Currant Extract
16. Black Tea Extract
17. Blueberry Extract
18. Chicory Extract
19. Citrus aurantium Extract
20. Carod tree fruit pods Extract
21. Coleus Forskohlii Extract
22. Cordydeps mycelia Extract
23. Coenzyme Q10/ CoQ10
24. Cat's claw Extract
25. Chamomile Extract
26. Cranberry Extract
27. Cytisine
28. Dihydromyricetin
29. Elderberry Extract
30. Echinacea Extract
31. Epimedium Extract
32. Evening primrose oil
33. Fenugreek seed Extract
34. Gingerols
35. Garden Burnet Extract
36. Ginkgo Biloba Extract
37. Garcinia Cambogia Extract
38. Green Coffee Bean Extract
39. Gynostemma Extract / Jiao gu lan Extract
40. Hawthorn Extract
41. Ivy Extract
42. Kava kava Extract
43. Lespedeza Capitata Extract
44. Luteolin
45. Luo Han Guo Extract
46. Marigold Extract / Lutein
47. Mangiferin
48. Mangosteen Extract
49. Maca Extract
50. Macleaya Cordata Extract
51. Milk Thistle Extract
52. Mulberry leaf Extract
53. Myricetin
54. Origanum Vulgare Leaf Extract
55. Oleanolic Acid
56. Pomegranate seed oil
57. Reishi spore oil
58. Resveratrol 98%
59. Red Clover Extract
60. Rosemary Extract
61. Saw Palmetto Extract
62. Sea buckthorn seed/berry oil and Extract
63. Stevia Leaf Extract
64. Turmeric Extract
65. Tomato Extract / Lycopene
66. Ursolic acid
67. Valerian Root Extract
68. Yacon Extract
69. Zeaxanthin
70. Zerumbone 98%
*Herbal Extract
* Herbal oil
*Natural color
*Herbal powder
*Vegetable & Fruit powder
*Softgel
*Vitamin & Mineral
*Pharmaceutical Application
*Food Supplement Application
Characteristic:
- We can also customize orders as customer's requirements and specifications.
- KINGHERBS' is specialized in manufacturing and exporting different kinds of food industry related goods, such as Artemisinin, Myricetin, Olive Leaf Extract Oleuropein 10%~80%, Hydroxytyrosol 5%-50%;
Olive Fruit Extract Maslinic Acid 5%~50% ; Dihydromyricetin, Sea Buckthorn Oil, Zinger Zerumbet Extract
Fenugreek Seed Extract Furostanol Saponins 50%, Apple Root extract, Rosemary Extract Rosmarinic Acid 2%~98%, Carnosic Acid 5%~80% etc
- With the effective exporting system and prompt reaction, we ensure that we can transfer the shipping documents and deliver our cargoes on time.
FAQ:
Q1. About Price:
The price is negotiable. It can be changed according to your quantity or package.
Q2. About Sample:
We can provide the typical size of samples, but the air freight is collect or you pay us the cost in advance.
Q3. About MOQ:
We have no provisions of MOQ, but usually 1KG.
Q4:About Delivery Time
Usually 5-10 days after payment
Contact Us
Office: 27Fl, Blding A, Cimen, Wanjiali Rd, Changsha 410014, Hunan, China
Tel: +86-138748 61871 , +86 731 89865683;
Fax: +86 731 89865681
Product Name: Maslinic acid
Botanical Source:Olea europaea L.
Part used: Fruit
Specification: Maslinic acid 10%,30%,60%, 98% HPLC
CAS No.: 4373-41-5
Appearance: Light yellow powder
Molecular Formula: C30H48O4
Molecular Weight: 472.7
Pharmacological action: Anti - tumor, anti - HIV, hawthorn acid can cause the spread of HIV in the body to reduce the risk of 80%. anti-inflammatory, antibacterial.
Scientists at the University of Granada in Spain found that Maslinic Acid can inhibit serine protease, HIV is using this enzyme will itself from infected cells to the external release and spread to the virus infected systemic.
Introduction
Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in the Mediterranean diet. In recent years, several studies have proved that maslinic acid exerts a wide range of biological activities, i.e. antitumor,
antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. Experimental models used for the assessment of maslinic acid effects include established cell lines, which have been often used to elucidate the underlying mechanisms of action, and also animal models of different disorders, which have confirmed the effects of the triterpene in vivo.
Aslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response.
Maslinic acid extracted from notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative agent against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM and CEM/ADR5000) cells (IC50 = 7 µM and 9 µM respectively).1,2,3,4 Maslinic acid · s antiproliferative activity likely comes from the induction of an oxidative apoptotic pathway, causing cell cycle and cytoskeleton alterations. Maslinic acid has been found to attenuate intracellular oxidative stress via inhibition of NO and H2O2 production and reduction of pro-inflammatory cytokine generation in murine macrophages.5 Recently maslinic acid has been found to inhibit the spread of the HIV virus by inhibiting the replication of a primary HIV-1 isolate as well as decreased the cytopathic effect and p24 antigen levels in MT2 cells.6
Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. Maslinic acid used was a white powder comprising 98% maslinic acid and 2% of oleanolic acid. This extract was stable when stored at 4 ºC It was dissolved before use at 10 mg/ml in 25% DMSO and 75% PBS. A stock solution was frozen and stored at -20 ºC.
Function:
Anti-oxidant
Anti-inflammatory
Anti-microbial
Anti-viral activities
Providing significant natural defense against colon-cancer
Restrain the conglomeration of blood platelet
As a dietary supplement to promote muscle growth
Reducing blood fat and pressure.
Be beneficial for diabetes
Inhibiting the spread of the HIV virus
| Analysis Items | Specifications | Results | Methods used |
| Identification | Positive | Conforms | TLC |
| Appearance | Fine Light Yellowish White Powder | Conforms | Visual Test |
| Odor & Taste | Characteristic | Conforms | Organoleptic Test |
| Bulk Density | 30-45g/100ml | Conforms | ASTM D1895B |
| Particle Size | NLT 98% through 80 mesh | Conforms | AOAC 973.03 |
| Solubility | Soluble in Ethanol, insoluble in Water | Conforms | Visual |
KINGHERBS' main products as below:
1.5-HTP
2. Acai Berry Extract
3. Acacia Catechu Extract
4. Allium cepa / Onion Extract
5. Aronia melanocarpa Extract
6. Artemisinin
7. Artichoke Extract
8. Astilbin
9. Apple Root Extract
10. Acerola Cherry Extract
11. Banaba Leaf Extract
12. Birch Leaf Extract
13. Birch Bark Extract
14. Bilberry Extract
15. Black Currant Extract
16. Black Tea Extract
17. Blueberry Extract
18. Chicory Extract
19. Citrus aurantium Extract
20. Carod tree fruit pods Extract
21. Coleus Forskohlii Extract
22. Cordydeps mycelia Extract
23. Coenzyme Q10/ CoQ10
24. Cat's claw Extract
25. Chamomile Extract
26. Cranberry Extract
27. Cytisine
28. Dihydromyricetin
29. Elderberry Extract
30. Echinacea Extract
31. Epimedium Extract
32. Evening primrose oil
33. Fenugreek seed Extract
34. Gingerols
35. Garden Burnet Extract
36. Ginkgo Biloba Extract
37. Garcinia Cambogia Extract
38. Green Coffee Bean Extract
39. Gynostemma Extract / Jiao gu lan Extract
40. Hawthorn Extract
41. Ivy Extract
42. Kava kava Extract
43. Lespedeza Capitata Extract
44. Luteolin
45. Luo Han Guo Extract
46. Marigold Extract / Lutein
47. Mangiferin
48. Mangosteen Extract
49. Maca Extract
50. Macleaya Cordata Extract
51. Milk Thistle Extract
52. Mulberry leaf Extract
53. Myricetin
54. Origanum Vulgare Leaf Extract
55. Oleanolic Acid
56. Pomegranate seed oil
57. Reishi spore oil
58. Resveratrol 98%
59. Red Clover Extract
60. Rosemary Extract
61. Saw Palmetto Extract
62. Sea buckthorn seed/berry oil and Extract
63. Stevia Leaf Extract
64. Turmeric Extract
65. Tomato Extract / Lycopene
66. Ursolic acid
67. Valerian Root Extract
68. Yacon Extract
69. Zeaxanthin
70. Zerumbone 98%
*Herbal Extract
* Herbal oil
*Natural color
*Herbal powder
*Vegetable & Fruit powder
*Softgel
*Vitamin & Mineral
*Pharmaceutical Application
*Food Supplement Application
Characteristic:
- We can also customize orders as customer's requirements and specifications.
- KINGHERBS' is specialized in manufacturing and exporting different kinds of food industry related goods, such as Artemisinin, Myricetin, Olive Leaf Extract Oleuropein 10%~80%, Hydroxytyrosol 5%-50%;
Olive Fruit Extract Maslinic Acid 5%~50% ; Dihydromyricetin, Sea Buckthorn Oil, Zinger Zerumbet Extract
Fenugreek Seed Extract Furostanol Saponins 50%, Apple Root extract, Rosemary Extract Rosmarinic Acid 2%~98%, Carnosic Acid 5%~80% etc
- With the effective exporting system and prompt reaction, we ensure that we can transfer the shipping documents and deliver our cargoes on time.
FAQ:
Q1. About Price:
The price is negotiable. It can be changed according to your quantity or package.
Q2. About Sample:
We can provide the typical size of samples, but the air freight is collect or you pay us the cost in advance.
Q3. About MOQ:
We have no provisions of MOQ, but usually 1KG.
Q4:About Delivery Time
Usually 5-10 days after payment
Contact Us
Office: 27Fl, Blding A, Cimen, Wanjiali Rd, Changsha 410014, Hunan, China
Tel: +86-138748 61871 , +86 731 89865683;
Fax: +86 731 89865681